Binders

Microcrystalline Cellulose, Ph.Eur., NF, JP

RO-CEP-2009-321

Air Stream Dried Quality	Spray Dried Quality	Average Particle Size by laser diffraction (µm)	Bulk Density (g/cm3)		Main Application
			VIVAPUR®	EMCOCEL®
VIVAPUR® 105		25	0.20 - 0.26		Very fine grade, which gives a pleasant mouth feeling, masks bitter tastes and supports flavors.
VIVAPUR® 101	EMCOCEL® 50M	65	0.26 - 0.31	0.25 - 0.37	Fine standard MCC grade, especially suited for wet granulation, roller compaction and spheronization. Very high compactibility.
VIVAPUR® 101 Premium		65	0.26 - 0.31		Same grade as 101 but very low amount of visable specks and high degree of bright-ness.
VIVAPUR® 103	EMCOCEL® LM50	65	0.26 - 0.34	0.25 - 0.37	Same quality as grade 101/50M, but very low moisture content (< 1.5% resp. 3%) for processing water-sensitive actives.
VIVAPUR® 301		65	0.35 - 0.46		Same quality as grade 101, but increased bulk density and improved flow properties.
VIVAPUR® 102	EMCOCEL® 90M	100	0.28 - 0.33	0.25 - 0.37	Medium size standard MCC grade, suited for the majority of directly compressible actives. Combines good flow and high compactibility.
VIVAPUR® 102 Premium		100	0.28 - 0.33		Same grade as 102 but very low amount of visable specks and high degree of bright-ness.
VIVAPUR® 112	EMCOCEL® XLM90	100	0.30 - 0.36	0.25 - 0.37	Same quality to grades 102/90M, but very low moisture content (< 1.5%) for pro-cessing water-sensitive actives.
VIVAPUR® 302	EMCOCEL® HD90	100	0.35 - 0.50	0.38 - 0.50	Same quality to grade 102/90M, but increased bulk density and improved flow properties. Especially suited for high speed tableting and processing high density actives.
The Innovative MCC- Grade for Direct Compression
VIVAPUR® 12		180	0.30 - 0.36		Coarse grade MCC, combines good compactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation - even when used with low concentrations of fine actives.
VIVAPUR® 14		180	0.34 - 0.42		Same quality to grade 12, but very low moisture content (<1,5%) for processing water-sensitive actives.
	EMCOCEL® LP200	190		0.25 - 0.37	Coarse grade MCC, combines good com-pactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation - even when used with low concentrations of fine actives.
VIVAPUR® 200		250	0.31 - 0.37		Large size MCC grade with excellent flow properties for a variety of direct compression formulations.
VIVAPUR® XLM200		250	0.33 - 0.40		Same quality to grades 200/LP200, but very low moisture content (<1,5%) for processing water-sensitive actives.